| 1. Round | 12/09/2020 | sc Heerenveen | - | Willem II | 2:0 |  |
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| 2. Round | 19/09/2020 | Fortuna Sittard | - | sc Heerenveen | 1:3 |  |
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| 3. Round | 26/09/2020 | sc Heerenveen | - | VVV-Venlo | 1:0 | ||||
| 4. Round | 02/10/2020 | FC Utrecht | - | sc Heerenveen | 1:1 | ||||
| 5. Round | 18/10/2020 | AFC Ajax | - | sc Heerenveen | 5:1 | ||||
| 6. Round | 24/10/2020 | sc Heerenveen | - | FC Emmen | 4:0 | ||||
| 7. Round | 01/11/2020 | Sparta Rotterdam | - | sc Heerenveen | 1:4 | ||||
| 8. Round | 08/11/2020 | sc Heerenveen | - | AZ Alkmaar | 0:3 | ||||
| 12. Round | 13/12/2020 | Vitesse | - | sc Heerenveen | 1:1 | ||||
| 13. Round | 20/12/2020 | sc Heerenveen | - | Heracles Almelo | 1:2 | ||||
| 14. Round | 23/12/2020 | Feyenoord | - | sc Heerenveen | 3:0 | ||||
| 15. Round | 10/01/2021 | sc Heerenveen | - | Fortuna Sittard | 1:3 | ||||
| 17. Round | 17/01/2021 | VVV-Venlo | - | sc Heerenveen | 1:1 | ||||
| 22. Round | 14/02/2021 | AZ Alkmaar | - | sc Heerenveen | 3:1 | ||||
| 24. Round | 26/02/2021 | PEC Zwolle | - | sc Heerenveen | 4:1 |
Germany
Brazil