| 4. Round | 17/08/2024 | 1. FC Bocholt | - | FC Schalke 04 II | 3:1 | ||||
| 5. Round | 24/08/2024 | FC Schalke 04 II | - | 1. FC Düren | 1:4 | ||||
| 6. Round | 01/09/2024 | 1. FC Köln II | - | FC Schalke 04 II | 4:0 | ||||
| 7. Round | 14/09/2024 | FC Schalke 04 II | - | Bor. Mönchengladbach II | 0:1 | ||||
| 9. Round | 28/09/2024 | FC Schalke 04 II | - | MSV Duisburg | 1:2 | ||||
| 10. Round | 05/10/2024 | Sportfreunde Lotte | - | FC Schalke 04 II | 4:1 | ||||
| 11. Round | 11/10/2024 | FC Schalke 04 II | - | FC Gütersloh | 1:1 | ||||
| 14. Round | 02/11/2024 | Eintracht Hohkeppel | - | FC Schalke 04 II | 2:1 | ||||
| 15. Round | 08/11/2024 | FC Schalke 04 II | - | SC Paderborn 07 II | 0:4 | ||||
| 12. Round | 15/11/2024 | Türkspor Dortmund | - | FC Schalke 04 II | annull. | ||||
| 18. Round | 07/12/2024 | FC Schalke 04 II | - | SC Wiedenbrück | 3:1 | ||||
| 20. Round | 01/02/2025 | SV Rödinghausen | - | FC Schalke 04 II | 0:0 | ||||
| 34. Round | 17/05/2025 | Fortuna Köln | - | FC Schalke 04 II | 3:0 |
Germany
Spain