| 7. Round | 10/10/2021 | TuS Erndtebrück | - | Preußen Münster II | 2:0 | ||||
| 8. Round | 17/10/2021 | SC Paderborn 07 II | - | TuS Erndtebrück | 5:0 | ||||
| 9. Round | 24/10/2021 | TuS Erndtebrück | - | RSV Meinerzhagen | 1:0 | ||||
| 10. Round | 31/10/2021 | Westfalia Herne | - | TuS Erndtebrück | 2:4 |  |
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| 11. Round | 07/11/2021 | TuS Erndtebrück | - | Westfalia Rhynern | 1:4 | ||||
| 12. Round | 14/11/2021 | Holzwickeder SC | - | TuS Erndtebrück | 0:6 | |
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| 15. Round | 05/12/2021 | TuS Erndtebrück | - | 1. FC Kaan-Marienborn | 2:1 | ||||
| 16. Round | 12/12/2021 | Viktoria Clarholz | - | TuS Erndtebrück | 2:2 | ||||
| 17. Round | 20/02/2022 | TuS Erndtebrück | - | TuS Ennepetal | 3:2 |  |
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| 18. Round | 06/03/2022 | SV Schermbeck | - | TuS Erndtebrück | 4:0 |
England
Nigeria