| 1. Round | 14/08/2021 | 1. FC 06 Erlensee | - | Hünfelder SV | 3:2 | ||||
| 2. Round | 21/08/2021 | SV Buchonia Flieden | - | 1. FC 06 Erlensee | 1:1 | ||||
| 3. Round | 28/08/2021 | 1. FC 06 Erlensee | - | FC Hanau 93 | 4:0 | ||||
| 5. Round | 04/09/2021 | Bayern Alzenau | - | 1. FC 06 Erlensee | 2:4 | ||||
| 6. Round | 11/09/2021 | 1. FC 06 Erlensee | - | SG Barockstadt Fulda-Lehnerz | 0:1 | ||||
| 7. Round | 15/09/2021 | 1. FC 06 Erlensee | - | SV Buchonia Flieden | 7:0 | ||||
| 9. Round | 26/09/2021 | SV Steinbach | - | 1. FC 06 Erlensee | 0:1 | ||||
| 10. Round | 29/09/2021 | FC Hanau 93 | - | 1. FC 06 Erlensee | 3:1 | ||||
| 11. Round | 03/10/2021 | 1. FC 06 Erlensee | - | SV 1910 Neuhof | 3:2 | ||||
| 12. Round | 09/10/2021 | Eintracht Stadtallendorf | - | 1. FC 06 Erlensee | 1:2 | ||||
| 13. Round | 16/10/2021 | 1. FC 06 Erlensee | - | FSV Fernwald | 3:1 |
Germany