| 1. Round | 18/03/2022 | SG Mülheim-Kärlich | - | TSG Pfeddersheim | 0:4 | ||||
| 1. Round | 26/03/2022 | FSV Jägersburg | - | SG Mülheim-Kärlich | 2:4 | ||||
| 2. Round | 10/04/2022 | SV 07 Elversberg II | - | SG Mülheim-Kärlich | 0:1 |  |
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| 2. Round | 16/04/2022 | SG Mülheim-Kärlich | - | SV Röchling Völklingen | annull. | ||||
| 2. Round | 20/04/2022 | SG Mülheim-Kärlich | - | FV Eppelborn | 2:1 | ||||
| 2. Round | 24/04/2022 | FC Speyer 09 | - | SG Mülheim-Kärlich | 1:1 | ||||
| 2. Round | 29/04/2022 | TSG Pfeddersheim | - | SG Mülheim-Kärlich | 3:0 | ||||
| 3. Round | 07/05/2022 | SG Mülheim-Kärlich | - | FSV Jägersburg | 0:2 | ||||
| 3. Round | 14/05/2022 | FV Eppelborn | - | SG Mülheim-Kärlich | 1:3 | |
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| 3. Round | 20/05/2022 | SG Mülheim-Kärlich | - | SV 07 Elversberg II | 2:4 |  |
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| 4. Round | 04/06/2022 | SG Mülheim-Kärlich | - | FC Speyer 09 | 2:0 | |
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Germany