| 7. Round | 04/09/2021 | SC Verl | - | FC Viktoria 1889 Berlin | 3:3 |  |
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| 8. Round | 11/09/2021 | FSV Zwickau | - | SC Verl | 1:3 | ||||
| 10. Round | 25/09/2021 | SC Verl | - | TSV 1860 München | 1:1 | ||||
| 11. Round | 03/10/2021 | Waldhof Mannheim | - | SC Verl | 2:1 | ||||
| 12. Round | 18/10/2021 | SC Verl | - | TSV Havelse | 5:3 | ||||
| 13. Round | 23/10/2021 | SC Freiburg II | - | SC Verl | 3:2 | |
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| 14. Round | 01/11/2021 | SC Verl | - | VfL Osnabrück | 1:2 | ||||
| 15. Round | 07/11/2021 | 1. FC Magdeburg | - | SC Verl | 2:0 | ||||
| 18. Round | 04/12/2021 | SC Verl | - | Borussia Dortmund II | 0:3 | ||||
| 19. Round | 11/12/2021 | MSV Duisburg | - | SC Verl | 2:2 | ||||
| 30. Round | 12/03/2022 | SC Verl | - | Waldhof Mannheim | 1:3 |
Germany