| 1. Round | 14/08/2021 | Viktoria Griesheim | - | SV Rot-Weiss Hadamar | 0:3 | ||||
| 6. Round | 11/09/2021 | Viktoria Griesheim | - | VfB Ginsheim | 3:0 | ||||
| 7. Round | 15/09/2021 | Viktoria Griesheim | - | Rot-Weiß Walldorf | 3:2 |  |
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| 9. Round | 25/09/2021 | TuS Dietkirchen | - | Viktoria Griesheim | 1:3 | |
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| 10. Round | 29/09/2021 | FC Eddersheim | - | Viktoria Griesheim | 2:5 | |
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| 11. Round | 02/10/2021 | Viktoria Griesheim | - | SC Waldgirmes | 1:3 | |
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| 12. Round | 08/10/2021 | Hessen Dreieich | - | Viktoria Griesheim | 3:1 | ||||
| 13. Round | 16/10/2021 | Viktoria Griesheim | - | Türk Gücü Friedberg | 0:0 | ||||
| 14. Round | 24/10/2021 | FV Bad Vilbel | - | Viktoria Griesheim | 0:3 | |
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| 15. Round | 27/10/2021 | Viktoria Griesheim | - | SV Zeilsheim | 4:1 | ||||
| 16. Round | 30/10/2021 | Viktoria Griesheim | - | FV Bad Vilbel | 2:3 | ||||
| 17. Round | 07/11/2021 | Türk Gücü Friedberg | - | Viktoria Griesheim | 2:3 | ||||
| 18. Round | 13/11/2021 | Viktoria Griesheim | - | Hessen Dreieich | 1:3 | ||||
| 19. Round | 20/11/2021 | SC Waldgirmes | - | Viktoria Griesheim | 2:0 | ||||
| 20. Round | 27/11/2021 | Viktoria Griesheim | - | TuS Dietkirchen | 1:2 | ||||
| 22. Round | 11/12/2021 | VfB Ginsheim | - | Viktoria Griesheim | 4:3 |
Germany