| 1. Round | 12/03/2022 | HSC/BW Tündern | - | TB Uphusen | 0:1 | ||||
| 2. Round | 19/03/2022 | TB Uphusen | - | MTV Gifhorn | 1:1 |  |
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| 4. Round | 03/04/2022 | TB Uphusen | - | Eintracht Northeim | 2:1 |  |
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| 5. Round | 09/04/2022 | MTV Wolfenbüttel | - | TB Uphusen | 1:2 | |
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| 3. Round | 18/04/2022 | TB Uphusen | - | SVG Göttingen 07 | 0:2 | ||||
| 6. Round | 23/04/2022 | TB Uphusen | - | HSC/BW Tündern | 2:1 | |
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| 7. Round | 30/04/2022 | MTV Gifhorn | - | TB Uphusen | 3:0 | |
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| 8. Round | 06/05/2022 | SVG Göttingen 07 | - | TB Uphusen | 3:1 | |
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| 10. Round | 14/05/2022 | Eintracht Northeim | - | TB Uphusen | 5:3 | ||||
| 9. Round | 21/05/2022 | TB Uphusen | - | MTV Wolfenbüttel | 2:5 |
Dom. Republic