| 4. Round | 11/09/2021 | FC St. Pauli [Youth B] | - | FC Carl Zeiss Jena [Youth B] | 4:0 | ||||
| 6. Round | 25/09/2021 | FC St. Pauli [Youth B] | - | 1. FC Union Berlin [Youth B] | 0:2 | ||||
| 7. Round | 02/10/2021 | Hannover 96 [Youth B] | - | FC St. Pauli [Youth B] | 0:0 | ||||
| 8. Round | 09/10/2021 | FC St. Pauli [Youth B] | - | Dynamo Dresden [Youth B] | 3:1 | ||||
| 9. Round | 30/10/2021 | FC Viktoria 1889 Berlin [Youth B] | - | FC St. Pauli [Youth B] | 0:1 | ||||
| 13. Round | 26/03/2022 | FC St. Pauli [Youth B] | - | Energie Cottbus [Youth B] | 2:0 | ||||
| 17. Round | 02/04/2022 | FC St. Pauli [Youth B] | - | Werder Bremen [Youth B] | 2:1 | ||||
| 16. Round | 05/04/2022 | Eintracht Braunschweig [Youth B] | - | FC St. Pauli [Youth B] | 0:2 | ||||
| 19. Round | 24/04/2022 | FC St. Pauli [Youth B] | - | Hamburger SV [Youth B] | 1:3 |
Germany