| 1. Round | 23/08/1980 | Dynamo Dresden | - | BSG Wismut Aue | 3:0 |  |
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| 2. Round | 30/08/1980 | FC Carl Zeiss Jena | - | Dynamo Dresden | 2:0 | ||||
| 3. Round | 06/09/1980 | Rot-Weiß Erfurt | - | Dynamo Dresden | 0:1 | ||||
| 4. Round | 13/09/1980 | Dynamo Dresden | - | HFC Chemie | 3:2 | ||||
| 5. Round | 20/09/1980 | FC Karl-Marx-Stadt | - | Dynamo Dresden | 1:2 | |
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| 6. Round | 27/09/1980 | Dynamo Dresden | - | BSG Sachsenring Zwickau | 3:2 | ||||
| 7. Round | 04/10/1980 | Hansa Rostock | - | Dynamo Dresden | 1:1 | |
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| 8. Round | 18/10/1980 | Dynamo Dresden | - | 1. FC Lokomotive Leipzig | 2:1 | ||||
| 10. Round | 08/11/1980 | Dynamo Dresden | - | FC Vorwärts Frankfurt/Oder | 3:1 | ||||
| 11. Round | 15/11/1980 | BFC Dynamo | - | Dynamo Dresden | 2:1 | |
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| 12. Round | 22/11/1980 | Dynamo Dresden | - | 1. FC Magdeburg | 3:1 | |
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| 13. Round | 29/11/1980 | BSG Stahl Riesa | - | Dynamo Dresden | 0:2 | |
Germany