| 1. Round | 08/08/2010 | 1. FC Nürnberg II | - | Wormatia Worms | 1:0 | ||||
| 2. Round | 12/08/2010 | FC Memmingen | - | 1. FC Nürnberg II | 2:1 | ||||
| 3. Round | 21/08/2010 | 1. FC Nürnberg II | - | SC Pfullendorf | 1:0 | ||||
| 5. Round | 31/08/2010 | 1. FC Nürnberg II | - | SV Darmstadt 98 | 0:1 |  |
|||
| 6. Round | 04/09/2010 | Stuttgarter Kickers | - | 1. FC Nürnberg II | 1:2 | ||||
| 7. Round | 10/09/2010 | SpVgg Weiden | - | 1. FC Nürnberg II | annull. | ||||
| 8. Round | 18/09/2010 | 1. FC Nürnberg II | - | 1899 Hoffenheim II | 1:2 | |
|||
| 9. Round | 21/09/2010 | TSV 1860 München II | - | 1. FC Nürnberg II | 5:2 | |
|||
| 11. Round | 01/10/2010 | SSV Ulm 1846 | - | 1. FC Nürnberg II | annull. | ||||
| 12. Round | 16/10/2010 | 1. FC Nürnberg II | - | SC Freiburg II | 3:0 | ||||
| 4. Round | 19/10/2010 | SG Sonnenhof Großaspach | - | 1. FC Nürnberg II | 0:2 | ||||
| 13. Round | 24/10/2010 | Hessen Kassel | - | 1. FC Nürnberg II | 0:0 | ||||
| 15. Round | 06/11/2010 | SpVgg Greuther Fürth II | - | 1. FC Nürnberg II | 6:1 | ||||
| 16. Round | 13/11/2010 | 1. FC Nürnberg II | - | Eintracht Frankfurt II | 2:3 |
Germany
