| 1. Round | 05/08/2022 | MSV 1919 Neuruppin | - | FC Mecklenburg Schwerin | 3:0 | ||||
| 2. Round | 14/08/2022 | FC Mecklenburg Schwerin | - | 1. FC Frankfurt (Oder) | 0:7 | ||||
| 7. Round | 02/10/2022 | TSG Neustrelitz | - | FC Mecklenburg Schwerin | 4:1 | ||||
| 12. Round | 06/11/2022 | SC Staaken | - | FC Mecklenburg Schwerin | 1:4 |  |
|||
| 13. Round | 12/11/2022 | FC Mecklenburg Schwerin | - | RSV Eintracht 1949 | 2:1 |  |
|||
| 14. Round | 25/11/2022 | Dynamo Schwerin | - | FC Mecklenburg Schwerin | 4:1 | ||||
| 16. Round | 10/12/2022 | Optik Rathenow | - | FC Mecklenburg Schwerin | 2:1 | ||||
| 23. Round | 04/03/2023 | Union Fürstenwalde | - | FC Mecklenburg Schwerin | 2:2 | ||||
| 17. Round | 08/03/2023 | FC Mecklenburg Schwerin | - | TuS Makkabi Berlin | 0:4 | ||||
| 26. Round | 31/03/2023 | FC Mecklenburg Schwerin | - | Hansa Rostock II | 1:4 |
Brazil