| 1. Round | 25/08/2018 | VfL Wolfsburg | - | FC Schalke 04 | 2:1 | ||||
| 2. Round | 02/09/2018 | FC Schalke 04 | - | Hertha BSC | 0:2 | ||||
| 3. Round | 15/09/2018 | Bor. Mönchengladbach | - | FC Schalke 04 | 2:1 | ||||
| 4. Round | 22/09/2018 | FC Schalke 04 | - | Bayern München | 0:2 | ||||
| 5. Round | 25/09/2018 | SC Freiburg | - | FC Schalke 04 | 1:0 | ||||
| 6. Round | 29/09/2018 | FC Schalke 04 | - | 1. FSV Mainz 05 | 1:0 | ||||
| 7. Round | 06/10/2018 | Fortuna Düsseldorf | - | FC Schalke 04 | 0:2 | ||||
| 11. Round | 11/11/2018 | Eintracht Frankfurt | - | FC Schalke 04 | 3:0 | ||||
| 12. Round | 24/11/2018 | FC Schalke 04 | - | 1. FC Nürnberg | 5:2 | ||||
| 13. Round | 01/12/2018 | 1899 Hoffenheim | - | FC Schalke 04 | 1:1 | ||||
| 14. Round | 08/12/2018 | FC Schalke 04 | - | Borussia Dortmund | 1:2 | ||||
| 15. Round | 15/12/2018 | FC Augsburg | - | FC Schalke 04 | 1:1 | ||||
| 16. Round | 19/12/2018 | FC Schalke 04 | - | Bayer Leverkusen | 1:2 | ||||
| 17. Round | 22/12/2018 | VfB Stuttgart | - | FC Schalke 04 | 1:3 | ||||
| 20. Round | 02/02/2019 | FC Schalke 04 | - | Bor. Mönchengladbach | 0:2 | ||||
| 21. Round | 09/02/2019 | Bayern München | - | FC Schalke 04 | 3:1 | ||||
| 22. Round | 16/02/2019 | FC Schalke 04 | - | SC Freiburg | 0:0 |
Germany
