| 2. Round | 06/09/1980 | ISG Schwerin | - | Chemie/Motor Veritas Wittenberge | 3:1 | ||||
| 3. Round | 13/09/1980 | Chemie/Motor Veritas Wittenberge | - | ASG Vorwärts Neubrandenburg | 1:0 | ||||
| 4. Round | 20/09/1980 | TSG Wismar | - | Chemie/Motor Veritas Wittenberge | 1:1 | ||||
| 5. Round | 04/10/1980 | Chemie/Motor Veritas Wittenberge | - | BSG Motor Wolgast | 0:0 | ||||
| 6. Round | 07/10/1980 | TSG Bau Rostock | - | Chemie/Motor Veritas Wittenberge | 2:1 | ||||
| 7. Round | 19/10/1980 | Chemie/Motor Veritas Wittenberge | - | SG Dynamo Schwerin | 0:3 | ||||
| 8. Round | 26/10/1980 | BSG Post Neubrandenburg | - | Chemie/Motor Veritas Wittenberge | 1:1 |  |
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| 9. Round | 08/11/1980 | Chemie/Motor Veritas Wittenberge | - | BSG KKW Greifswald | 3:1 | ||||
| 10. Round | 15/11/1980 | Chemie/Motor Veritas Wittenberge | - | BSG Lok Anklam | 0:1 | ||||
| 11. Round | 22/11/1980 | ASG Vorwärts Stralsund | - | Chemie/Motor Veritas Wittenberge | 5:0 | ||||
| 12. Round | 29/11/1980 | BSG Schiffahrt/Hafen Rostock | - | Chemie/Motor Veritas Wittenberge | 4:0 |
Germany