| 2. Round | 15/12/2021 | PSV Eindhoven | - | Fortuna Sittard | 2:0 |  |
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| Round of 16 | 20/01/2022 | PSV Eindhoven | - | Telstar | 2:1 | ||||
| Quarter-finals | 08/02/2022 | PSV Eindhoven | - | NAC Breda | 4:0 | ||||
| Semi-finals | 02/03/2022 | Go Ahead Eagles | - | PSV Eindhoven | 1:2 | ||||
| Final | 17/04/2022 | PSV Eindhoven | - | AFC Ajax | 2:1 |
Japan