| 3. Round | 05/09/2021 | SC Union Nettetal | - | Schwarz-Weiß Essen | 1:3 |  |
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| 4. Round | 12/09/2021 | Schwarz-Weiß Essen | - | SC Düsseldorf-West | 5:1 | ||||
| 8. Round | 10/10/2021 | Schwarz-Weiß Essen | - | 1. FC Bocholt | 0:3 | ||||
| 10. Round | 24/10/2021 | Schwarz-Weiß Essen | - | TVD Velbert | 5:1 | ||||
| 16. Round | 12/12/2021 | Germania Ratingen 04/19 | - | Schwarz-Weiß Essen | 5:0 |
Germany