| 7. Round | 04/10/1980 | FC Carl Zeiss Jena | - | 1. FC Magdeburg | 2:3 | ||||
| 9. Round | 25/10/1980 | BSG Sachsenring Zwickau | - | 1. FC Magdeburg | 0:1 |  |
|||
| 10. Round | 08/11/1980 | 1. FC Magdeburg | - | 1. FC Lokomotive Leipzig | 4:1 | ||||
| 11. Round | 15/11/1980 | FC Vorwärts Frankfurt/Oder | - | 1. FC Magdeburg | 1:2 | ||||
| 12. Round | 22/11/1980 | Dynamo Dresden | - | 1. FC Magdeburg | 3:1 | |
|||
| 13. Round | 29/11/1980 | 1. FC Magdeburg | - | BSG Wismut Aue | 4:1 | ||||
| 14. Round | 21/02/1981 | 1. FC Magdeburg | - | Rot-Weiß Erfurt | 1:2 |  |
|||
| 15. Round | 28/02/1981 | FC Karl-Marx-Stadt | - | 1. FC Magdeburg | 1:1 | ||||
| 19. Round | 28/03/1981 | BSG Stahl Riesa | - | 1. FC Magdeburg | 2:1 | ||||
| 20. Round | 11/04/1981 | 1. FC Magdeburg | - | FC Carl Zeiss Jena | 3:1 | ||||
| 21. Round | 15/04/1981 | HFC Chemie | - | 1. FC Magdeburg | 1:1 | ||||
| 23. Round | 09/05/1981 | 1. FC Lokomotive Leipzig | - | 1. FC Magdeburg | 1:1 | ||||
| 24. Round | 16/05/1981 | 1. FC Magdeburg | - | FC Vorwärts Frankfurt/Oder | 4:1 | ||||
| 25. Round | 23/05/1981 | 1. FC Magdeburg | - | Dynamo Dresden | 1:2 | ||||
| 26. Round | 30/05/1981 | BSG Wismut Aue | - | 1. FC Magdeburg | 2:1 |
Germany