| 5. Round | 14/08/2021 | SV Lichtenberg 47 | - | Hertha BSC II | 0:0 | ||||
| 6. Round | 18/08/2021 | Hertha BSC II | - | Chemnitzer FC | 1:0 | ||||
| 9. Round | 31/08/2021 | Hertha BSC II | - | BFC Dynamo | 2:3 | ||||
| 10. Round | 10/09/2021 | Optik Rathenow | - | Hertha BSC II | 2:2 | ||||
| 4. Round | 22/09/2021 | Hertha BSC II | - | SV Babelsberg 03 | 0:3 | ||||
| 13. Round | 03/10/2021 | Hertha BSC II | - | TeBe Berlin | 0:1 | ||||
| 27. Round | 25/02/2022 | Hertha BSC II | - | FSV 63 Luckenwalde | 4:0 | ||||
| 29. Round | 11/03/2022 | Hertha BSC II | - | Optik Rathenow | 2:0 | ||||
| 31. Round | 01/04/2022 | Hertha BSC II | - | VfB Auerbach | 3:0 | ||||
| 32. Round | 06/04/2022 | TeBe Berlin | - | Hertha BSC II | 0:4 | ||||
| 33. Round | 10/04/2022 | Hertha BSC II | - | Union Fürstenwalde | 5:0 | ||||
| 34. Round | 16/04/2022 | Berliner AK 07 | - | Hertha BSC II | 2:2 | ||||
| 35. Round | 22/04/2022 | Hertha BSC II | - | VSG Altglienicke | 1:1 | ||||
| 36. Round | 30/04/2022 | 1. FC Lok Leipzig | - | Hertha BSC II | 0:2 | ||||
| 37. Round | 08/05/2022 | Hertha BSC II | - | Energie Cottbus | 1:1 | ||||
| 38. Round | 15/05/2022 | FC Eilenburg | - | Hertha BSC II | 2:3 |
Germany