| 21. Round | 23/02/2019 | FK Pirmasens | - | 1899 Hoffenheim II | 0:4 | ||||
| 22. Round | 01/03/2019 | 1899 Hoffenheim II | - | Kickers Offenbach | 0:5 |  |
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| 24. Round | 13/03/2019 | 1899 Hoffenheim II | - | FC 08 Homburg | 0:2 | ||||
| 25. Round | 16/03/2019 | SV 07 Elversberg | - | 1899 Hoffenheim II | 1:0 | ||||
| 27. Round | 29/03/2019 | 1. FSV Mainz 05 II | - | 1899 Hoffenheim II | 2:2 | ||||
| 28. Round | 06/04/2019 | 1899 Hoffenheim II | - | SSV Ulm 1846 | 0:4 | ||||
| 26. Round | 09/04/2019 | 1899 Hoffenheim II | - | FC-Astoria Walldorf | 2:0 |  |
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| 29. Round | 14/04/2019 | VfB Stuttgart II | - | 1899 Hoffenheim II | 0:0 | ||||
| 30. Round | 20/04/2019 | Hessen Dreieich | - | 1899 Hoffenheim II | 1:4 | ||||
| 32. Round | 04/05/2019 | SC Freiburg II | - | 1899 Hoffenheim II | 3:1 | |
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| 33. Round | 12/05/2019 | 1899 Hoffenheim II | - | 1. FC Saarbrücken | 0:3 | ||||
| 34. Round | 18/05/2019 | Eintracht Stadtallendorf | - | 1899 Hoffenheim II | 4:1 | |
Germany