| 3. Round | 14/08/2021 | Dynamo Dresden | - | Hannover 96 | 2:0 |  |
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| 4. Round | 21/08/2021 | Hansa Rostock | - | Dynamo Dresden | 1:3 | ||||
| 5. Round | 29/08/2021 | Dynamo Dresden | - | SC Paderborn 07 | 0:3 | ||||
| 6. Round | 12/09/2021 | 1. FC Heidenheim 1846 | - | Dynamo Dresden | 2:1 |  |
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| 7. Round | 19/09/2021 | SV Darmstadt 98 | - | Dynamo Dresden | 1:0 | ||||
| 10. Round | 17/10/2021 | Dynamo Dresden | - | 1. FC Nürnberg | 0:1 | ||||
| 11. Round | 23/10/2021 | FC Schalke 04 | - | Dynamo Dresden | 3:0 | ||||
| 12. Round | 30/10/2021 | Dynamo Dresden | - | SV Sandhausen | 0:1 | ||||
| 21. Round | 06/02/2022 | Dynamo Dresden | - | Hansa Rostock | 1:4 | ||||
| 22. Round | 12/02/2022 | SC Paderborn 07 | - | Dynamo Dresden | 0:0 | ||||
| 23. Round | 18/02/2022 | Dynamo Dresden | - | 1. FC Heidenheim 1846 | 1:1 | ||||
| 24. Round | 26/02/2022 | Dynamo Dresden | - | SV Darmstadt 98 | 0:1 | ||||
| 25. Round | 06/03/2022 | Werder Bremen | - | Dynamo Dresden | 2:1 | ||||
| 28. Round | 01/04/2022 | Dynamo Dresden | - | FC Schalke 04 | 1:2 | ||||
| 29. Round | 10/04/2022 | SV Sandhausen | - | Dynamo Dresden | 2:1 | ||||
| 30. Round | 16/04/2022 | Dynamo Dresden | - | Holstein Kiel | 0:0 |
Germany