| 3. Round | 18/08/2012 | 1. FSV Mainz 05 II | - | SC Pfullendorf | 2:4 | ||||
| 4. Round | 21/08/2012 | SC Freiburg II | - | 1. FSV Mainz 05 II | 1:1 |  |
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| 5. Round | 25/08/2012 | 1. FC Eschborn | - | 1. FSV Mainz 05 II | 2:1 | |
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| 6. Round | 01/09/2012 | 1. FSV Mainz 05 II | - | FC 08 Homburg | 1:3 | ||||
| 7. Round | 04/09/2012 | Eintracht Frankfurt II | - | 1. FSV Mainz 05 II | 0:1 | ||||
| 8. Round | 11/09/2012 | 1. FSV Mainz 05 II | - | FSV Frankfurt II | 2:0 | ||||
| 9. Round | 15/09/2012 | Wormatia Worms | - | 1. FSV Mainz 05 II | 1:4 |  |
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| 10. Round | 23/09/2012 | 1. FSV Mainz 05 II | - | SC 07 Idar-Oberstein | 1:1 | |
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| 14. Round | 20/10/2012 | 1. FSV Mainz 05 II | - | Hessen Kassel | 4:4 | |
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| 23. Round | 24/02/2013 | 1. FSV Mainz 05 II | - | SC Freiburg II | 2:1 |
Germany
USA