| 22. Round | 09/02/2022 | BSG Chemie Leipzig | - | ZFC Meuselwitz | 0:0 |  |
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| 25. Round | 12/02/2022 | SV Lichtenberg 47 | - | BSG Chemie Leipzig | 2:1 | ||||
| 26. Round | 19/02/2022 | BSG Chemie Leipzig | - | Hertha BSC II | 2:1 | ||||
| 27. Round | 25/02/2022 | Chemnitzer FC | - | BSG Chemie Leipzig | 1:0 | ||||
| 28. Round | 05/03/2022 | FSV 63 Luckenwalde | - | BSG Chemie Leipzig | 5:3 | ||||
| 35. Round | 24/04/2022 | BSG Chemie Leipzig | - | Berliner AK 07 | 0:2 | |
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| 36. Round | 29/04/2022 | VSG Altglienicke | - | BSG Chemie Leipzig | 2:3 |
Germany