| 2. Round | 04/08/2007 | VfR Aalen | - | Karlsruher SC II | 2:0 | ||||
| 3. Round | 12/08/2007 | Karlsruher SC II | - | SSV Reutlingen | 0:0 | ||||
| 15. Round | 10/11/2007 | VfB Stuttgart II | - | Karlsruher SC II | 2:1 | ||||
| 23. Round | 22/03/2008 | Karlsruher SC II | - | SpVgg Unterhaching | 0:1 | ||||
| 27. Round | 19/04/2008 | Karlsruher SC II | - | Jahn Regensburg | 1:0 | ||||
| 28. Round | 26/04/2008 | SC Pfullendorf | - | Karlsruher SC II | 0:0 | ||||
| 29. Round | 02/05/2008 | Karlsruher SC II | - | Sportfreunde Siegen | 1:2 | ||||
| 30. Round | 06/05/2008 | Bayern München II | - | Karlsruher SC II | 3:1 | ||||
| 31. Round | 09/05/2008 | Karlsruher SC II | - | Hessen Kassel | 6:1 | ||||
| 32. Round | 17/05/2008 | Karlsruher SC II | - | VfB Stuttgart II | 0:5 | ||||
| 33. Round | 24/05/2008 | SV Sandhausen | - | Karlsruher SC II | 1:0 | ||||
| 34. Round | 31/05/2008 | Karlsruher SC II | - | FSV Oggersheim | 1:0 |  |
Germany