| 1. Round | 14/08/2021 | TuS Dietkirchen | - | FV Bad Vilbel | 2:0 |  |
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| 2. Round | 21/08/2021 | SV Rot-Weiss Hadamar | - | TuS Dietkirchen | 3:2 | |
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| 3. Round | 28/08/2021 | TuS Dietkirchen | - | Rot-Weiß Walldorf | 5:2 | ||||
| 5. Round | 05/09/2021 | FC Eddersheim | - | TuS Dietkirchen | 2:2 | ||||
| 6. Round | 11/09/2021 | TuS Dietkirchen | - | SV Zeilsheim | 0:1 | ||||
| 7. Round | 15/09/2021 | TuS Dietkirchen | - | SV Rot-Weiss Hadamar | 4:1 | |
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| 8. Round | 19/09/2021 | VfB Ginsheim | - | TuS Dietkirchen | 1:1 | |
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| 9. Round | 25/09/2021 | TuS Dietkirchen | - | Viktoria Griesheim | 1:3 | ||||
| 10. Round | 28/09/2021 | Rot-Weiß Walldorf | - | TuS Dietkirchen | 4:3 | ||||
| 12. Round | 09/10/2021 | SC Waldgirmes | - | TuS Dietkirchen | 3:4 | |
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| 20. Round | 27/11/2021 | Viktoria Griesheim | - | TuS Dietkirchen | 1:2 | ||||
| 21. Round | 04/12/2021 | TuS Dietkirchen | - | VfB Ginsheim | 2:1 | |
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| 22. Round | 11/12/2021 | SV Zeilsheim | - | TuS Dietkirchen | 1:3 |
Germany