| 2. Round | 21/08/2021 | RB Leipzig [Youth B] | - | Chemnitzer FC [Youth B] | 1:2 | ||||
| 12. Round | 27/11/2021 | Hansa Rostock [Youth B] | - | Chemnitzer FC [Youth B] | 0:2 | ||||
| 14. Round | 26/02/2022 | Chemnitzer FC [Youth B] | - | FC Carl Zeiss Jena [Youth B] | 2:1 | ||||
| 15. Round | 05/03/2022 | Hallescher FC [Youth B] | - | Chemnitzer FC [Youth B] | 0:2 | ||||
| 17. Round | 26/03/2022 | Hannover 96 [Youth B] | - | Chemnitzer FC [Youth B] | 2:1 | ||||
| 18. Round | 09/04/2022 | Chemnitzer FC [Youth B] | - | Dynamo Dresden [Youth B] | 1:0 |
Germany