| 16. Round | 04/02/2018 | 1. FC Nürnberg [Youth] | - | Karlsruher SC [Youth] | 2:1 | ||||
| 17. Round | 11/02/2018 | Karlsruher SC [Youth] | - | VfB Stuttgart [Youth] | 2:0 | ||||
| 18. Round | 17/02/2018 | Eintracht Frankfurt [Youth] | - | Karlsruher SC [Youth] | 1:0 | ||||
| 19. Round | 24/02/2018 | Karlsruher SC [Youth] | - | 1. FC Heidenheim 1846 [Youth] | 1:0 | ||||
| 20. Round | 03/03/2018 | 1899 Hoffenheim [Youth] | - | Karlsruher SC [Youth] | 2:2 |  |
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| 21. Round | 10/03/2018 | Karlsruher SC [Youth] | - | SV Wehen Wiesbaden [Youth] | 4:1 | ||||
| 22. Round | 07/04/2018 | FC Augsburg [Youth] | - | Karlsruher SC [Youth] | 1:3 | ||||
| 23. Round | 14/04/2018 | Karlsruher SC [Youth] | - | SC Freiburg [Youth] | 0:0 | ||||
| 24. Round | 22/04/2018 | Karlsruher SC [Youth] | - | SpVgg Unterhaching [Youth] | 3:1 |  |
Germany