| 1. Round | 14/08/2021 | 1. FC Saarbrücken [Youth] | - | 1. FC Heidenheim 1846 [Youth] | 1:2 | ||||
| 4. Round | 18/09/2021 | SSV Ulm 1846 [Youth] | - | 1. FC Saarbrücken [Youth] | 2:1 | ||||
| 5. Round | 25/09/2021 | 1. FC Saarbrücken [Youth] | - | Bayern München [Youth] | 1:5 | ||||
| 6. Round | 02/10/2021 | FC Augsburg [Youth] | - | 1. FC Saarbrücken [Youth] | 0:1 | ||||
| 10. Round | 20/11/2021 | 1. FC Saarbrücken [Youth] | - | 1899 Hoffenheim [Youth] | 1:3 | ||||
| 11. Round | 28/11/2021 | Hessen Kassel [Youth] | - | 1. FC Saarbrücken [Youth] | 0:2 | ||||
| 14. Round | 13/02/2022 | 1. FC Saarbrücken [Youth] | - | 1. FSV Mainz 05 [Youth] | 0:2 | ||||
| 18. Round | 03/04/2022 | 1. FC Saarbrücken [Youth] | - | SpVgg Unterhaching [Youth] | 2:1 | ||||
| 19. Round | 20/04/2022 | 1. FC Kaiserslautern [Youth] | - | 1. FC Saarbrücken [Youth] | 5:0 | ||||
| 21. Round | 30/04/2022 | SV Darmstadt 98 [Youth] | - | 1. FC Saarbrücken [Youth] | 0:2 |
Germany