| 1. Round | 13/03/2022 | U.S.I. Lupo-Martini | - | Heeslinger SC | 1:2 | ||||
| 2. Round | 20/03/2022 | Blau-Weiß Lohne | - | U.S.I. Lupo-Martini | 1:0 | ||||
| 3. Round | 27/03/2022 | U.S.I. Lupo-Martini | - | VfL Oldenburg | 2:2 | ||||
| 4. Round | 03/04/2022 | SC Spelle-Venhaus | - | U.S.I. Lupo-Martini | 3:1 | ||||
| 5. Round | 10/04/2022 | U.S.I. Lupo-Martini | - | Kickers Emden | 2:2 | ||||
| 6. Round | 24/04/2022 | Heeslinger SC | - | U.S.I. Lupo-Martini | 2:1 | ||||
| 7. Round | 01/05/2022 | U.S.I. Lupo-Martini | - | Blau-Weiß Lohne | 1:0 | ||||
| 8. Round | 08/05/2022 | VfL Oldenburg | - | U.S.I. Lupo-Martini | 4:2 |
Germany