| 8. Round | 10/09/2022 | SC Paderborn 07 | - | Jahn Regensburg | 3:0 |  |
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| 12. Round | 16/10/2022 | SC Paderborn 07 | - | SV Sandhausen | 3:0 | ||||
| 13. Round | 22/10/2022 | Eintracht Braunschweig | - | SC Paderborn 07 | 0:0 | |
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| 18. Round | 27/01/2023 | Karlsruher SC | - | SC Paderborn 07 | 0:1 | |
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| 19. Round | 03/02/2023 | SC Paderborn 07 | - | Fortuna Düsseldorf | 4:1 | ||||
| 21. Round | 17/02/2023 | SC Paderborn 07 | - | 1. FC Kaiserslautern | 1:0 | ||||
| 22. Round | 25/02/2023 | Holstein Kiel | - | SC Paderborn 07 | 1:1 | ||||
| 23. Round | 03/03/2023 | SC Paderborn 07 | - | FC St. Pauli | 1:2 | ||||
| 24. Round | 11/03/2023 | 1. FC Magdeburg | - | SC Paderborn 07 | 0:0 | ||||
| 25. Round | 18/03/2023 | Jahn Regensburg | - | SC Paderborn 07 | 1:0 | ||||
| 26. Round | 02/04/2023 | SC Paderborn 07 | - | SpVgg Greuther Fürth | 3:2 | ||||
| 27. Round | 09/04/2023 | SV Darmstadt 98 | - | SC Paderborn 07 | 2:1 | ||||
| 30. Round | 28/04/2023 | SC Paderborn 07 | - | Eintracht Braunschweig | 5:1 | |
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| 31. Round | 05/05/2023 | Hamburger SV | - | SC Paderborn 07 | 2:2 | ||||
| 33. Round | 20/05/2023 | Arminia Bielefeld | - | SC Paderborn 07 | 2:2 | ||||
| 34. Round | 28/05/2023 | SC Paderborn 07 | - | 1. FC Nürnberg | 0:1 |
Germany