| 1. Round | 22/08/2021 | TV Jahn Hiesfeld | - | FC Kray | 1:4 | ||||
| 2. Round | 29/08/2021 | DJK Teutonia St. Tönis | - | TV Jahn Hiesfeld | 4:1 | ||||
| 4. Round | 10/09/2021 | Germania Ratingen 04/19 | - | TV Jahn Hiesfeld | 0:0 | ||||
| 5. Round | 19/09/2021 | TV Jahn Hiesfeld | - | 1. FC Monheim | 0:2 | ||||
| 7. Round | 03/10/2021 | TV Jahn Hiesfeld | - | FSV Duisburg | 0:0 | ||||
| 8. Round | 10/10/2021 | VfB 03 Hilden | - | TV Jahn Hiesfeld | 1:0 | ||||
| 9. Round | 17/10/2021 | TV Jahn Hiesfeld | - | SC Velbert | 2:1 | ||||
| 10. Round | 24/10/2021 | Sportfreunde Niederwenigern | - | TV Jahn Hiesfeld | 1:2 | ||||
| 12. Round | 07/11/2021 | TV Jahn Hiesfeld | - | SpVg Schonnebeck | 0:3 |
Germany