| 1. Round | 14/08/2022 | FC St. Pauli [Youth B] | - | 1. FC Union Berlin [Youth B] | 1:0 |  |
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| 2. Round | 20/08/2022 | Hamburger SV [Youth B] | - | FC St. Pauli [Youth B] | 1:1 | ||||
| 3. Round | 27/08/2022 | FC St. Pauli [Youth B] | - | SV Meppen [Youth B] | 3:2 | |
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| 4. Round | 03/09/2022 | Erzgebirge Aue [Youth B] | - | FC St. Pauli [Youth B] | 0:2 | ||||
| 6. Round | 24/09/2022 | 1. FC Magdeburg [Youth B] | - | FC St. Pauli [Youth B] | 2:4 | ||||
| 7. Round | 02/10/2022 | FC St. Pauli [Youth B] | - | Niendorfer TSV [Youth B] | 1:1 | ||||
| 8. Round | 08/10/2022 | VfL Wolfsburg [Youth B] | - | FC St. Pauli [Youth B] | 2:0 | ||||
| 9. Round | 29/10/2022 | FC St. Pauli [Youth B] | - | RB Leipzig [Youth B] | 1:3 | |
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| 10. Round | 05/11/2022 | Werder Bremen [Youth B] | - | FC St. Pauli [Youth B] | 1:1 | ||||
| 11. Round | 12/11/2022 | FC St. Pauli [Youth B] | - | FC Viktoria 1889 Berlin [Youth B] | 3:0 | ||||
| 12. Round | 19/11/2022 | Hansa Rostock [Youth B] | - | FC St. Pauli [Youth B] | 2:1 | ||||
| 13. Round | 03/12/2022 | FC St. Pauli [Youth B] | - | Dynamo Dresden [Youth B] | 0:3 | ||||
| 14. Round | 10/12/2022 | Hannover 96 [Youth B] | - | FC St. Pauli [Youth B] | 2:3 |
Germany