| 1. Round | 05/08/2022 | MSV 1919 Neuruppin | - | FC Mecklenburg Schwerin | 3:0 | ||||
| 3. Round | 20/08/2022 | Rostocker FC | - | FC Mecklenburg Schwerin | 6:1 | ||||
| 4. Round | 26/08/2022 | FC Mecklenburg Schwerin | - | MSV Pampow | 0:2 | ||||
| 19. Round | 05/02/2023 | 1. FC Frankfurt (Oder) | - | FC Mecklenburg Schwerin | 1:5 | ||||
| 23. Round | 04/03/2023 | Union Fürstenwalde | - | FC Mecklenburg Schwerin | 2:2 | ||||
| 27. Round | 15/04/2023 | Blau-Weiß 90 Berlin | - | FC Mecklenburg Schwerin | 4:1 | ||||
| 28. Round | 23/04/2023 | CFC Hertha 06 | - | FC Mecklenburg Schwerin | 2:1 | ||||
| 30. Round | 06/05/2023 | RSV Eintracht 1949 | - | FC Mecklenburg Schwerin | 3:1 | ||||
| 32. Round | 27/05/2023 | FC Mecklenburg Schwerin | - | SV Tasmania Berlin | 6:1 |  |
Germany