| 1. Round | 15/08/2021 | FC Carl Zeiss Jena [Youth] | - | VfL Osnabrück [Youth] | 0:0 | ||||
| 2. Round | 21/08/2021 | Holstein Kiel [Youth] | - | FC Carl Zeiss Jena [Youth] | 2:1 | ||||
| 3. Round | 11/09/2021 | FC Carl Zeiss Jena [Youth] | - | RB Leipzig [Youth] | 0:1 | ||||
| 4. Round | 18/09/2021 | Chemnitzer FC [Youth] | - | FC Carl Zeiss Jena [Youth] | 1:1 | ||||
| 5. Round | 25/09/2021 | FC Carl Zeiss Jena [Youth] | - | Eimsbütteler TV [Youth] | 4:1 | ||||
| 6. Round | 02/10/2021 | Dynamo Dresden [Youth] | - | FC Carl Zeiss Jena [Youth] | 4:0 | ||||
| 7. Round | 17/10/2021 | FC Carl Zeiss Jena [Youth] | - | FC Viktoria 1889 Berlin [Youth] | 0:1 | ||||
| 8. Round | 23/10/2021 | Hallescher FC [Youth] | - | FC Carl Zeiss Jena [Youth] | 3:1 | ||||
| 9. Round | 30/10/2021 | FC Carl Zeiss Jena [Youth] | - | VfL Wolfsburg [Youth] | 1:3 |
Germany