| 6. Round | 25/09/2021 | Energie Cottbus [Youth B] | - | Hallescher FC [Youth B] | 1:2 | ||||
| 7. Round | 02/10/2021 | 1. FC Union Berlin [Youth B] | - | Energie Cottbus [Youth B] | 3:1 | ||||
| 8. Round | 09/10/2021 | Energie Cottbus [Youth B] | - | Hannover 96 [Youth B] | 2:1 |  |
|||
| 10. Round | 06/11/2021 | Energie Cottbus [Youth B] | - | FC Viktoria 1889 Berlin [Youth B] | 2:1 | ||||
| 3. Round | 13/11/2021 | Hansa Rostock [Youth B] | - | Energie Cottbus [Youth B] | 5:2 | ||||
| 11. Round | 20/11/2021 | Erzgebirge Aue [Youth B] | - | Energie Cottbus [Youth B] | 2:2 | ||||
| 5. Round | 23/02/2022 | FC Carl Zeiss Jena [Youth B] | - | Energie Cottbus [Youth B] | 2:0 | ||||
| 12. Round | 02/03/2022 | Energie Cottbus [Youth B] | - | RB Leipzig [Youth B] | 0:6 |
Germany