1st(1st leg) FC Utrecht - Zenit St. Petersburg 1:0 (0:0)
2nd (2nd leg) Zenit St. Petersburg - FC Utrecht 2:0 (1:0, 1:0) aet
1st(1st leg): 16/08/2017 17:00 2nd (2nd leg): 24/08/2017 18:00 Winner: Zenit St. Petersburg
1st(1st leg) Apollon Limassol - FC Midtjylland 3:2 (1:1)
2nd (2nd leg) FC Midtjylland - Apollon Limassol 1:1 (1:0)
1st(1st leg): 17/08/2017 18:00 2nd (2nd leg): 24/08/2017 19:00 Winner: Apollon Limassol
1st(1st leg) FK Krasnodar - Crvena Zvezda 3:2 (1:0)
2nd (2nd leg) Crvena Zvezda - FK Krasnodar 2:1 (1:0)
1st(1st leg): 17/08/2017 18:00 2nd (2nd leg): 24/08/2017 20:00 Winner: Crvena Zvezda
1st(1st leg) BATE Borisov - FC Oleksandriya 1:1 (1:1)
2nd (2nd leg) FC Oleksandriya - BATE Borisov 1:2 (1:0)
1st(1st leg): 17/08/2017 18:00 2nd (2nd leg): 24/08/2017 18:00 Winner: BATE Borisov
1st(1st leg) Dinamo Zagreb - KF Skënderbeu 1:1 (0:1)
2nd (2nd leg) KF Skënderbeu - Dinamo Zagreb 0:0 (0:0)
1st(1st leg): 17/08/2017 18:00 2nd (2nd leg): 24/08/2017 19:00 Winner: KF Skënderbeu
1st(1st leg) FH Hafnarfjörður - Sporting Braga 1:2 (1:0)
2nd (2nd leg) Sporting Braga - FH Hafnarfjörður 3:2 (1:1)
1st(1st leg): 17/08/2017 18:45 2nd (2nd leg): 24/08/2017 19:45 Winner: Sporting Braga
1st(1st leg) Vardar Skopje - Fenerbahçe 2:0 (1:0)
2nd (2nd leg) Fenerbahçe - Vardar Skopje 1:2 (0:0)
1st(1st leg): 17/08/2017 19:00 2nd (2nd leg): 24/08/2017 18:30 Winner: Vardar Skopje
1st(1st leg) PAOK Saloniki - Östersunds FK 3:1 (1:1)
2nd (2nd leg) Östersunds FK - PAOK Saloniki 2:0 (0:0)
1st(1st leg): 17/08/2017 19:00 2nd (2nd leg): 24/08/2017 18:00 Winner: Östersunds FK
1st(1st leg) Viktoria Plzeň - AEK Larnaca 3:1 (2:1)
2nd (2nd leg) AEK Larnaca - Viktoria Plzeň 0:0 (0:0)
1st(1st leg): 17/08/2017 19:15 2nd (2nd leg): 24/08/2017 17:00 Winner: Viktoria Plzeň
1st(1st leg) Panathinaikos - Athletic Bilbao 2:3 (1:0)
2nd (2nd leg) Athletic Bilbao - Panathinaikos 1:0 (1:0)
1st(1st leg): 17/08/2017 19:30 2nd (2nd leg): 24/08/2017 19:45 Winner: Athletic Bilbao
1st(1st leg) SCR Altach - Maccabi Tel Aviv 0:1 (0:0)
2nd (2nd leg) Maccabi Tel Aviv - SCR Altach 2:2 (1:1)
1st(1st leg): 17/08/2017 19:30 2nd (2nd leg): 24/08/2017 18:00 Winner: Maccabi Tel Aviv
1st(1st leg) PFC Ludogorets Razgrad - FK Sūduva 2:0 (0:0)
2nd (2nd leg) FK Sūduva - PFC Ludogorets Razgrad 0:0 (0:0)
1st(1st leg): 17/08/2017 19:30 2nd (2nd leg): 24/08/2017 18:30 Winner: PFC Ludogorets Razgrad
1st(1st leg) AC Milan - KF Shkëndija 79 6:0 (3:0)
2nd (2nd leg) KF Shkëndija 79 - AC Milan 0:1 (0:1)
1st(1st leg): 17/08/2017 19:45 2nd (2nd leg): 24/08/2017 19:45 Winner: AC Milan
1st(1st leg) NK Osijek - Austria Wien 1:2 (1:1)
2nd (2nd leg) Austria Wien - NK Osijek 0:1 (0:0)
1st(1st leg): 17/08/2017 19:45 2nd (2nd leg): 24/08/2017 20:05 Winner: Austria Wien
1st(1st leg) AFC Ajax - Rosenborg BK 0:1 (0:0)
2nd (2nd leg) Rosenborg BK - AFC Ajax 3:2 (1:0)
1st(1st leg): 17/08/2017 19:45 2nd (2nd leg): 24/08/2017 19:45 Winner: Rosenborg BK
1st(1st leg) Club Brugge KV - AEK Athen 0:0 (0:0)
2nd (2nd leg) AEK Athen - Club Brugge KV 3:0 (2:0)
1st(1st leg): 17/08/2017 19:45 2nd (2nd leg): 24/08/2017 19:00 Winner: AEK Athen
1st(1st leg) NK Domžale - Olympique Marseille 1:1 (1:0)
2nd (2nd leg) Olympique Marseille - NK Domžale 3:0 (1:0)
1st(1st leg): 17/08/2017 19:45 2nd (2nd leg): 24/08/2017 19:45 Winner: Olympique Marseille
1st(1st leg) Legia Warszawa - FC Sheriff 1:1 (0:0)
2nd (2nd leg) FC Sheriff - Legia Warszawa 0:0 (0:0)
1st(1st leg): 17/08/2017 19:45 2nd (2nd leg): 24/08/2017 18:00 Winner: FC Sheriff
1st(1st leg) FC Viitorul Constanța - RB Salzburg 1:3 (1:3)
2nd (2nd leg) RB Salzburg - FC Viitorul Constanța 4:0 (2:0)
1st(1st leg): 17/08/2017 19:45 2nd (2nd leg): 24/08/2017 18:00 Winner: RB Salzburg
1st(1st leg) Partizan - Videoton FC 0:0 (0:0)
2nd (2nd leg) Videoton FC - Partizan 0:4 (0:3)
1st(1st leg): 17/08/2017 20:00 2nd (2nd leg): 24/08/2017 19:00 Winner: Partizan
1st(1st leg) Everton FC - Hajduk Split 2:0 (2:0)
2nd (2nd leg) Hajduk Split - Everton FC 1:1 (1:0)
1st(1st leg): 17/08/2017 20:05 2nd (2nd leg): 24/08/2017 20:00 Winner: Everton FC
1st(1st leg) CS Marítimo - Dinamo Kiev 0:0 (0:0)
2nd (2nd leg) Dinamo Kiev - CS Marítimo 3:1 (2:0)
1st(1st leg): 17/08/2017 20:30 2nd (2nd leg): 24/08/2017 17:45 Winner: Dinamo Kiev