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| 1st(1st leg) | VfL Wolfsburg | - | ACF Brescia | 3:0 (1:0) | ||
| 2nd (2nd leg) | ACF Brescia | - | VfL Wolfsburg | 0:3 (0:2) | ||
| 1st(1st leg): 23/03/2016 17:00 | 2nd (2nd leg): 30/03/2016 19:30 | Winner: VfL Wolfsburg | ||||
| 1st(1st leg) | FC Barcelona | - | Paris Saint-Germain | 0:0 (0:0) | ||
| 2nd (2nd leg) | Paris Saint-Germain | - | FC Barcelona | 1:0 (0:0) | ||
| 1st(1st leg): 23/03/2016 17:30 | 2nd (2nd leg): 30/03/2016 19:30 | Winner: Paris Saint-Germain | ||||
| 1st(1st leg) | Olympique Lyonnais | - | Slavia Praha | 9:1 (4:1) | ||
| 2nd (2nd leg) | Slavia Praha | - | Olympique Lyonnais | 0:0 (0:0) | ||
| 1st(1st leg): 23/03/2016 18:00 | 2nd (2nd leg): 30/03/2016 17:30 | Winner: Olympique Lyonnais | ||||
| 1st(1st leg) | FC Rosengård | - | 1. FFC Frankfurt | 0:1 (0:0) | ||
| 2nd (2nd leg) | 1. FFC Frankfurt | - | FC Rosengård | 5:4 (0:1, 0:1, 0:1) pso | ||
| 1st(1st leg): 23/03/2016 19:00 | 2nd (2nd leg): 30/03/2016 17:00 | Winner: 1. FFC Frankfurt | ||||
