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| 1st(1st leg) | Girondins Bordeaux | - | Roda JC Kerkrade | 1:0 (0:0) | ||
| 2nd (2nd leg) | Roda JC Kerkrade | - | Girondins Bordeaux | 2:0 (0:0) | ||
| 1st(1st leg): 20/11/2001 17:00 | 2nd (2nd leg): 04/12/2001 17:00 | Winner: Roda JC Kerkrade | ||||
| 1st(1st leg) | Hapoel Tel Aviv | - | Lokomotiv Moskva | 2:1 (1:0) | ||
| 2nd (2nd leg) | Lokomotiv Moskva | - | Hapoel Tel Aviv | 0:1 (0:0) | ||
| 1st(1st leg): 20/11/2001 17:00 | 2nd (2nd leg): 04/12/2001 17:00 | Winner: Hapoel Tel Aviv | ||||
| 1st(1st leg) | Servette FC | - | Hertha BSC | 0:0 (0:0) | ||
| 2nd (2nd leg) | Hertha BSC | - | Servette FC | 0:3 (0:1) | ||
| 1st(1st leg): 22/11/2001 17:00 | 2nd (2nd leg): 06/12/2001 17:00 | Winner: Servette FC | ||||
| 1st(1st leg) | FC København | - | Borussia Dortmund | 0:1 (0:0) | ||
| 2nd (2nd leg) | Borussia Dortmund | - | FC København | 1:0 (0:0) | ||
| 1st(1st leg): 22/11/2001 17:15 | 2nd (2nd leg): 04/12/2001 17:00 | Winner: Borussia Dortmund | ||||
| 1st(1st leg) | PAOK Saloniki | - | PSV Eindhoven | 3:2 (3:1) | ||
| 2nd (2nd leg) | PSV Eindhoven | - | PAOK Saloniki | 4:1 (2:0) | ||
| 1st(1st leg): 22/11/2001 17:30 | 2nd (2nd leg): 06/12/2001 18:30 | Winner: PSV Eindhoven | ||||
| 1st(1st leg) | Parma AC | - | Brøndby IF | 1:1 (1:0) | ||
| 2nd (2nd leg) | Brøndby IF | - | Parma AC | 0:3 (0:1) | ||
| 1st(1st leg): 22/11/2001 17:30 | 2nd (2nd leg): 06/12/2001 16:30 | Winner: Parma AC | ||||
| 1st(1st leg) | Slovan Liberec | - | RCD Mallorca | 3:1 (2:0) | ||
| 2nd (2nd leg) | RCD Mallorca | - | Slovan Liberec | 1:2 (0:0) | ||
| 1st(1st leg): 22/11/2001 18:00 | 2nd (2nd leg): 06/12/2001 19:45 | Winner: Slovan Liberec | ||||
| 1st(1st leg) | Club Brugge KV | - | Olympique Lyonnais | 4:1 (1:0) | ||
| 2nd (2nd leg) | Olympique Lyonnais | - | Club Brugge KV | 3:0 (2:0) | ||
| 1st(1st leg): 22/11/2001 18:30 | 2nd (2nd leg): 06/12/2001 18:30 | Winner: Olympique Lyonnais | ||||
| 1st(1st leg) | AEK Athen | - | PFC Litex Lovech | 3:2 (3:1) | ||
| 2nd (2nd leg) | PFC Litex Lovech | - | AEK Athen | 1:1 (0:1) | ||
| 1st(1st leg): 22/11/2001 19:15 | 2nd (2nd leg): 06/12/2001 17:00 | Winner: AEK Athen | ||||
| 1st(1st leg) | Grasshopper Club Zürich | - | Leeds United | 1:2 (1:0) | ||
| 2nd (2nd leg) | Leeds United | - | Grasshopper Club Zürich | 2:2 (2:1) | ||
| 1st(1st leg): 22/11/2001 19:15 | 2nd (2nd leg): 06/12/2001 20:00 | Winner: Leeds United | ||||
| 1st(1st leg) | Feyenoord | - | SC Freiburg | 1:0 (0:0) | ||
| 2nd (2nd leg) | SC Freiburg | - | Feyenoord | 2:2 (1:0) | ||
| 1st(1st leg): 22/11/2001 19:30 | 2nd (2nd leg): 06/12/2001 19:30 | Winner: Feyenoord | ||||
| 1st(1st leg) | ACF Fiorentina | - | Lille OSC | 0:1 (0:1) | ||
| 2nd (2nd leg) | Lille OSC | - | ACF Fiorentina | 2:0 (1:0) | ||
| 1st(1st leg): 22/11/2001 19:45 | 2nd (2nd leg): 06/12/2001 18:00 | Winner: Lille OSC | ||||
| 1st(1st leg) | Ipswich Town | - | Inter | 1:0 (0:0) | ||
| 2nd (2nd leg) | Inter | - | Ipswich Town | 4:1 (2:0) | ||
| 1st(1st leg): 22/11/2001 19:45 | 2nd (2nd leg): 06/12/2001 20:00 | Winner: Inter | ||||
| 1st(1st leg) | AC Milan | - | Sporting CP | 2:0 (1:0) | ||
| 2nd (2nd leg) | Sporting CP | - | AC Milan | 1:1 (0:0) | ||
| 1st(1st leg): 22/11/2001 19:45 | 2nd (2nd leg): 06/12/2001 20:00 | Winner: AC Milan | ||||
| 1st(1st leg) | Rangers FC | - | Paris Saint-Germain | 0:0 (0:0) | ||
| 2nd (2nd leg) | Paris Saint-Germain | - | Rangers FC | 3:4 (0:0, 0:0, 0:0) pso | ||
| 1st(1st leg): 22/11/2001 20:00 | 2nd (2nd leg): 06/12/2001 20:00 | Winner: Rangers FC | ||||
| 1st(1st leg) | Valencia CF | - | Celtic FC | 1:0 (0:0) | ||
| 2nd (2nd leg) | Celtic FC | - | Valencia CF | 4:5 (1:0, 1:0, 1:0) pso | ||
| 1st(1st leg): 22/11/2001 20:30 | 2nd (2nd leg): 06/12/2001 19:30 | Winner: Valencia CF | ||||
