| Group H | 04/11/2020 | RB Leipzig | - | Paris Saint-Germain | 2:1 | ||||
| Group H | 24/11/2020 | Paris Saint-Germain | - | RB Leipzig | 1:0 | ||||
| Group H | 02/12/2020 | İstanbul Başakşehir | - | RB Leipzig | 3:4 | ||||
| Group H | 08/12/2020 | RB Leipzig | - | Manchester United | 3:2 |  |
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| Round of 16 | 16/02/2021 | RB Leipzig | - | Liverpool FC | 0:2 |  |
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| Round of 16 | 10/03/2021 | Liverpool FC | - | RB Leipzig | 2:0 |
Mali