| 1. Round | 07/08/2021 | 1. FC Bruchsal | - | SV Linx | 0:2 | ||||
| 5. Round | 01/09/2021 | 1. FC Bruchsal | - | Freiburger FC | 2:2 | ||||
| 6. Round | 04/09/2021 | TSV Ilshofen | - | 1. FC Bruchsal | 2:2 | ||||
| 8. Round | 15/09/2021 | 1. FC Bruchsal | - | FSV 08 Bietigheim-Bissingen | 0:4 | ||||
| 9. Round | 18/09/2021 | Göppinger SV | - | 1. FC Bruchsal | 4:1 | ||||
| 10. Round | 25/09/2021 | 1. FC Bruchsal | - | FV Lörrach-Brombach | 2:1 | ||||
| 11. Round | 01/10/2021 | FC Nöttingen | - | 1. FC Bruchsal | 6:1 | ||||
| 12. Round | 09/10/2021 | 1. FC Bruchsal | - | SV Oberachern | 0:2 |  |
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| 13. Round | 16/10/2021 | Stuttgarter Kickers | - | 1. FC Bruchsal | 3:0 | |
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| 14. Round | 22/10/2021 | 1. FC Bruchsal | - | FC-Astoria Walldorf II | 1:0 | ||||
| 15. Round | 30/10/2021 | SGV Freiberg | - | 1. FC Bruchsal | 6:1 | ||||
| 16. Round | 06/11/2021 | 1. FC Bruchsal | - | SSV Reutlingen | 1:2 | ||||
| 18. Round | 20/11/2021 | 1. FC Bruchsal | - | FV Ravensburg | 2:2 | ||||
| 32. Round | 27/04/2022 | 1. FC Bruchsal | - | Stuttgarter Kickers | 2:2 | ||||
| 35. Round | 14/05/2022 | SSV Reutlingen | - | 1. FC Bruchsal | 0:3 dec. |
Germany