| 2. Round | 15/11/1980 | AFC Ajax | - | SVV Schiedam | 3:0 | ||||
| Round of 16 | 24/01/1981 | AFC Ajax | - | FC Twente | 5:1 |  |
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| Quarter-finals | 24/02/1981 | AFC Ajax | - | FC Groningen | 3:0 | ||||
| Quarter-finals | 17/03/1981 | FC Groningen | - | AFC Ajax | 1:1 | ||||
| Semi-finals | 14/04/1981 | PSV Eindhoven | - | AFC Ajax | 2:2 | |
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| Semi-finals | 04/05/1981 | AFC Ajax | - | PSV Eindhoven | 2:1 |  |
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| Final | 27/05/1981 | AFC Ajax | - | AZ '67 Alkmaar | 1:3 |
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