| 12. Round | 09/10/2021 | SSV Ulm 1846 | - | FK Pirmasens | 3:0 | ||||
| 23. Round | 18/12/2021 | FK Pirmasens | - | FC Gießen | 2:1 | ||||
| 26. Round | 26/02/2022 | VfB Stuttgart II | - | FK Pirmasens | 2:1 | ||||
| 27. Round | 05/03/2022 | FK Pirmasens | - | FSV Frankfurt | 0:1 | ||||
| 28. Round | 11/03/2022 | FC 08 Homburg | - | FK Pirmasens | 2:1 | ||||
| 37. Round | 07/05/2022 | FK Pirmasens | - | TSV Schott Mainz | 2:1 |
Germany