| 3. Round | 10/08/2019 | FC Schalke 04 II | - | SV Lippstadt 08 | 1:1 |  |
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| 4. Round | 17/08/2019 | Bonner SC | - | FC Schalke 04 II | 0:0 | ||||
| 5. Round | 24/08/2019 | Fortuna Düsseldorf II | - | FC Schalke 04 II | 2:1 | ||||
| 6. Round | 31/08/2019 | FC Schalke 04 II | - | SC Verl | 0:2 | ||||
| 7. Round | 06/09/2019 | Bor. Mönchengladbach II | - | FC Schalke 04 II | 4:1 |  |
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| 8. Round | 15/09/2019 | FC Schalke 04 II | - | Fortuna Köln | 1:0 | ||||
| 9. Round | 20/09/2019 | SV Bergisch Gladbach 09 | - | FC Schalke 04 II | 0:3 | ||||
| 11. Round | 28/09/2019 | Sportfreunde Lotte | - | FC Schalke 04 II | 2:1 | ||||
| 12. Round | 05/10/2019 | FC Schalke 04 II | - | Wuppertaler SV | 3:0 | ||||
| 13. Round | 12/10/2019 | Alemannia Aachen | - | FC Schalke 04 II | 0:1 | ||||
| 14. Round | 19/10/2019 | FC Schalke 04 II | - | TuS Haltern | 1:2 | ||||
| 15. Round | 26/10/2019 | Borussia Dortmund II | - | FC Schalke 04 II | 1:5 | ||||
| 1. Round | 29/10/2019 | FC Schalke 04 II | - | Rot-Weiß Oberhausen | 1:1 | ||||
| 16. Round | 02/11/2019 | FC Schalke 04 II | - | VfB Homberg | 4:0 | |
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| 18. Round | 16/11/2019 | FC Schalke 04 II | - | SV Rödinghausen | 1:2 | |
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| 10. Round | 23/11/2019 | FC Schalke 04 II | - | Rot-Weiss Essen | 0:0 |
Germany