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| 15/09/2021 | 18:30 | TSV Assamstadt | - | SV Wagenschwend | 0:1 | |
| 29/09/2021 | 18:15 | GU-Türkspor Pforzheim | - | Türkspor Mannheim | 1:2 | |
| 05/10/2021 | 18:00 | 1. CfR Pforzheim | - | 1. FC Bruchsal | 2:3 pso | |
| 10/11/2021 | 18:00 | FC Zuzenhausen | - | Waldhof Mannheim | 1:3 |
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| 15/09/2021 | 18:30 | TSV Assamstadt | - | SV Wagenschwend | 0:1 | |
| 29/09/2021 | 18:15 | GU-Türkspor Pforzheim | - | Türkspor Mannheim | 1:2 | |
| 05/10/2021 | 18:00 | 1. CfR Pforzheim | - | 1. FC Bruchsal | 2:3 pso | |
| 10/11/2021 | 18:00 | FC Zuzenhausen | - | Waldhof Mannheim | 1:3 |
