1st(1st leg) Sporting CP - İstanbul Başakşehir F.K. 3:1 (2:0)
2nd (2nd leg) İstanbul Başakşehir F.K. - Sporting CP 4:1 (2:0, 3:1) aet
1st(1st leg): 20/02/2020 17:55 2nd (2nd leg): 27/02/2020 17:55 Winner: İstanbul Başakşehir F.K.
1st(1st leg) Getafe CF - AFC Ajax 2:0 (1:0)
2nd (2nd leg) AFC Ajax - Getafe CF 2:1 (1:1)
1st(1st leg): 20/02/2020 17:55 2nd (2nd leg): 27/02/2020 20:00 Winner: Getafe CF
1st(1st leg) FC København - Celtic FC 1:1 (0:1)
2nd (2nd leg) Celtic FC - FC København 1:3 (0:0)
1st(1st leg): 20/02/2020 17:55 2nd (2nd leg): 27/02/2020 20:00 Winner: FC København
1st(1st leg) CFR Cluj - Sevilla FC 1:1 (0:0)
2nd (2nd leg) Sevilla FC - CFR Cluj 0:0 (0:0)
1st(1st leg): 20/02/2020 17:55 2nd (2nd leg): 27/02/2020 20:00 Winner: Sevilla FC
1st(1st leg) Club Brugge KV - Manchester United 1:1 (1:1)
2nd (2nd leg) Manchester United - Club Brugge KV 5:0 (3:0)
1st(1st leg): 20/02/2020 17:55 2nd (2nd leg): 27/02/2020 20:00 Winner: Manchester United
1st(1st leg) PFC Ludogorets Razgrad - Inter 0:2 (0:0)
2nd (2nd leg) Inter - PFC Ludogorets Razgrad 2:1 (2:1)
1st(1st leg): 20/02/2020 17:55 2nd (2nd leg): 27/02/2020 20:00 Winner: Inter
1st(1st leg) Eintracht Frankfurt - RB Salzburg 4:1 (2:0)
2nd (2nd leg) RB Salzburg - Eintracht Frankfurt 2:2 (1:1)
1st(1st leg): 20/02/2020 17:55 2nd (2nd leg): 28/02/2020 17:00 Winner: Eintracht Frankfurt
1st(1st leg) Shakhtar Donetsk - SL Benfica 2:1 (0:0)
2nd (2nd leg) SL Benfica - Shakhtar Donetsk 3:3 (2:1)
1st(1st leg): 20/02/2020 17:55 2nd (2nd leg): 27/02/2020 20:00 Winner: Shakhtar Donetsk
1st(1st leg) Wolverhampton Wanderers - Espanyol Barcelona 4:0 (1:0)
2nd (2nd leg) Espanyol Barcelona - Wolverhampton Wanderers 3:2 (1:1)
1st(1st leg): 20/02/2020 20:00 2nd (2nd leg): 27/02/2020 17:55 Winner: Wolverhampton Wanderers
1st(1st leg) Bayer Leverkusen - FC Porto 2:1 (1:0)
2nd (2nd leg) FC Porto - Bayer Leverkusen 1:3 (0:1)
1st(1st leg): 20/02/2020 20:00 2nd (2nd leg): 27/02/2020 17:55 Winner: Bayer Leverkusen
1st(1st leg) APOEL Nikosia - FC Basel 0:3 (0:1)
2nd (2nd leg) FC Basel - APOEL Nikosia 1:0 (1:0)
1st(1st leg): 20/02/2020 20:00 2nd (2nd leg): 27/02/2020 17:55 Winner: FC Basel
1st(1st leg) Olympiakos Piräus - Arsenal FC 0:1 (0:0)
2nd (2nd leg) Arsenal FC - Olympiakos Piräus 1:2 (0:0, 0:1) aet
1st(1st leg): 20/02/2020 20:00 2nd (2nd leg): 27/02/2020 20:00 Winner: Olympiakos Piräus
1st(1st leg) AZ Alkmaar - LASK 1:1 (0:1)
2nd (2nd leg) LASK - AZ Alkmaar 2:0 (1:0)
1st(1st leg): 20/02/2020 20:00 2nd (2nd leg): 27/02/2020 17:55 Winner: LASK
1st(1st leg) VfL Wolfsburg - Malmö FF 2:1 (0:0)
2nd (2nd leg) Malmö FF - VfL Wolfsburg 0:3 (0:1)
1st(1st leg): 20/02/2020 20:00 2nd (2nd leg): 27/02/2020 17:55 Winner: VfL Wolfsburg
1st(1st leg) AS Roma - KAA Gent 1:0 (1:0)
2nd (2nd leg) KAA Gent - AS Roma 1:1 (1:1)
1st(1st leg): 20/02/2020 20:00 2nd (2nd leg): 27/02/2020 17:55 Winner: AS Roma
1st(1st leg) Rangers FC - Sporting Braga 3:2 (0:1)
2nd (2nd leg) Sporting Braga - Rangers FC 0:1 (0:0)
1st(1st leg): 20/02/2020 20:00 2nd (2nd leg): 26/02/2020 17:00 Winner: Rangers FC