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| 1st(1st leg) | Olympique Lyon | - | ASD Torres Calcio | 3:0 (2:0) | ||
| 2nd (2nd leg) | ASD Torres Calcio | - | Olympique Lyon | 1:0 (1:0) | ||
| 1st(1st leg): 10/03/2010 16:30 | 2nd (2nd leg): 17/03/2010 14:00 | Winner: Olympique Lyon | ||||
| 1st(1st leg) | Umeå IK FF | - | Montpellier HSC | 0:0 (0:0) | ||
| 2nd (2nd leg) | Montpellier HSC | - | Umeå IK FF | 2:2 (0:0) | ||
| 1st(1st leg): 10/03/2010 18:00 | 2nd (2nd leg): 17/03/2010 18:00 | Winner: Umeå IK FF | ||||
| 1st(1st leg) | Turbine Potsdam | - | Røa IL | 5:0 (2:0) | ||
| 2nd (2nd leg) | Røa IL | - | Turbine Potsdam | 0:5 (0:1) | ||
| 1st(1st leg): 10/03/2010 18:00 | 2nd (2nd leg): 17/03/2010 14:30 | Winner: Turbine Potsdam | ||||
| 1st(1st leg) | FCR 2001 Duisburg | - | Arsenal LFC | 2:1 (1:0) | ||
| 2nd (2nd leg) | Arsenal LFC | - | FCR 2001 Duisburg | 0:2 (0:0) | ||
| 1st(1st leg): 10/03/2010 18:30 | 2nd (2nd leg): 14/03/2010 13:00 | Winner: FCR 2001 Duisburg | ||||
