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| 19/02/2022 | SGV Freiberg | - | SV Oberachern | 3:0 dec. | ||
| 13:00 | 1. CfR Pforzheim | - | Sportfreunde Dorfmerkingen | 4:1 (1:1) | ||
| 13:00 | FC-Astoria Walldorf II | - | Stuttgarter Kickers | 0:3 (0:2) | ||
| 13:00 | FV Ravensburg | - | Göppinger SV | 1:3 (1:2) | ||
| 13:00 | Neckarsulmer Sport-Union | - | Freiburger FC | 2:1 (1:1) | ||
| 13:00 | SSV Reutlingen | - | FC Nöttingen | 0:1 (0:1) | ||
| 13:00 | TSG Backnang | - | FV Lörrach-Brombach | 4:0 (0:0) | ||
| 20/02/2022 | 13:00 | 1. FC Rielasingen-Arlen | - | TSV Ilshofen | 2:2 (1:2) | |
| 23/03/2022 | 18:00 | FC 08 Villingen | - | FSV 08 Bietigheim-Bissingen | 2:2 (1:1) | |
| 18:00 | SV Linx | - | 1. FC Bruchsal | 4:2 (1:1) |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SGV Freiberg | 20 | 15 | 4 | 1 | 68:15 | 53 | 49 |
| 2 |
|
Stuttgarter Kickers | 20 | 15 | 2 | 3 | 46:13 | 33 | 47 |
| 3 |
|
Göppinger SV | 20 | 11 | 4 | 5 | 36:28 | 8 | 37 |
| 4 |
|
TSG Backnang | 20 | 11 | 2 | 7 | 45:29 | 16 | 35 |
| 5 |
|
1. CfR Pforzheim | 20 | 11 | 2 | 7 | 34:26 | 8 | 35 |
| 6 |
|
FC 08 Villingen | 20 | 10 | 3 | 7 | 35:25 | 10 | 33 |
| 7 |
|
FSV 08 Bietigheim-Bissingen | 20 | 8 | 6 | 6 | 40:25 | 15 | 30 |
| 8 |
|
FV Ravensburg | 20 | 7 | 8 | 5 | 40:31 | 9 | 29 |
| 9 |
|
SSV Reutlingen | 20 | 8 | 5 | 7 | 31:28 | 3 | 29 |
| 10 |
|
FC Nöttingen | 20 | 9 | 2 | 9 | 39:38 | 1 | 29 |
| 11 |
|
1. FC Rielasingen-Arlen | 20 | 8 | 5 | 7 | 24:25 | -1 | 29 |
| 12 |
|
SV Oberachern | 20 | 9 | 1 | 10 | 38:39 | -1 | 28 |
| 13 |
|
Neckarsulmer Sport-Union | 20 | 8 | 4 | 8 | 27:31 | -4 | 28 |
| 14 |
|
FC-Astoria Walldorf II | 20 | 8 | 3 | 9 | 29:37 | -8 | 27 |
| 15 |
|
SV Linx | 20 | 7 | 4 | 9 | 22:43 | -21 | 25 |
| 16 |
|
Freiburger FC | 20 | 5 | 4 | 11 | 25:34 | -9 | 19 |
| 17 |
|
1. FC Bruchsal | 20 | 5 | 3 | 12 | 23:47 | -24 | 18 |
| 18 |
|
Sportfreunde Dorfmerkingen | 20 | 4 | 4 | 12 | 21:47 | -26 | 16 |
| 19 |
|
TSV Ilshofen | 20 | 3 | 4 | 13 | 21:48 | -27 | 13 |
| 20 |
|
FV Lörrach-Brombach | 20 | 1 | 4 | 15 | 13:48 | -35 | 7 |
| Promotion | |
| Playoffs | |
| Relegation |
