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| 29/04/2022 | 18:30 | 1. FC Monheim | - | TVD Velbert | 1:1 (1:1) | |
| 19:00 | 1. FC Kleve | - | Sportfreunde Baumberg | 3:1 (3:0) | ||
| 30/04/2022 | 14:30 | 1. FC Bocholt | - | SpVg Schonnebeck | 3:0 (0:0) | |
| 15:30 | VfB 03 Hilden | - | TSV Meerbusch | 5:2 (2:0) | ||
| 17:00 | Schwarz-Weiß Essen | - | Germania Ratingen 04/19 | 2:2 (1:1) |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Bocholt | 27 | 21 | 5 | 1 | 88:19 | 69 | 68 |
| 2 |
|
VfB 03 Hilden | 27 | 21 | 3 | 3 | 73:25 | 48 | 66 |
| 3 |
|
SSVg Velbert | 26 | 21 | 3 | 2 | 68:20 | 48 | 66 |
| 4 |
|
Sportfreunde Baumberg | 27 | 17 | 2 | 8 | 68:39 | 29 | 53 |
| 5 |
|
1. FC Kleve | 27 | 13 | 6 | 8 | 57:39 | 18 | 45 |
| 6 |
|
TVD Velbert | 27 | 13 | 6 | 8 | 43:36 | 7 | 45 |
| 7 |
|
Germania Ratingen 04/19 | 26 | 13 | 5 | 8 | 60:40 | 20 | 44 |
| 8 |
|
1. FC Monheim | 27 | 12 | 6 | 9 | 45:34 | 11 | 42 |
| 9 |
|
Schwarz-Weiß Essen | 26 | 11 | 4 | 11 | 50:51 | -1 | 37 |
| 10 |
|
SpVg Schonnebeck | 26 | 10 | 6 | 10 | 47:43 | 4 | 36 |
| 11 |
|
TSV Meerbusch | 26 | 10 | 4 | 12 | 45:62 | -17 | 34 |
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