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| 06/10/2000 | 1. FSV Mainz 05 II | - | FK Pirmasens | 2:1 | ||
| 07/10/2000 | Rot-Weiß Hasborn | - | Sportfreunde Eisbachtal | 0:1 | ||
| SC 07 Idar-Oberstein | - | EGC Wirges | 0:0 | |||
| Germania Metternich | - | Wormatia Worms | 2:1 | |||
| 1. FC Saarbrücken II | - | VfL Hamm/Sieg | 0:1 | |||
| SC Halberg Brebach | - | FC 08 Homburg | 2:1 | |||
| 08/10/2000 | Borussia Neunkirchen | - | TuS Koblenz | 0:1 | ||
| Hassia Bingen | - | Eintracht Bad Kreuznach | 1:1 | |||
| FSV Salmrohr | - | SV Mettlach | 0:0 | |||
| 09/10/2000 | SC Hauenstein | - | 1. FC Kaiserslautern II | 0:1 |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Kaiserslautern II | 15 | 10 | 4 | 1 | 38:10 | 28 | 34 |
| 2 |
|
EGC Wirges | 15 | 9 | 3 | 3 | 37:18 | 19 | 30 |
| 3 |
|
FK Pirmasens | 16 | 8 | 4 | 4 | 25:14 | 11 | 28 |
| 4 |
|
TuS Koblenz | 16 | 7 | 6 | 3 | 26:13 | 13 | 27 |
| 5 |
|
VfL Hamm/Sieg | 15 | 9 | 0 | 6 | 27:18 | 9 | 27 |
| 6 |
|
SC Hauenstein | 15 | 8 | 2 | 5 | 24:18 | 6 | 26 |
| 7 |
|
Sportfreunde Eisbachtal | 16 | 7 | 5 | 4 | 23:23 | 0 | 26 |
| 8 |
|
Eintracht Bad Kreuznach | 15 | 7 | 4 | 4 | 23:17 | 6 | 25 |
| 9 |
|
Borussia Neunkirchen | 15 | 7 | 3 | 5 | 30:16 | 14 | 24 |
| 10 |
|
FSV Salmrohr | 16 | 6 | 6 | 4 | 21:16 | 5 | 24 |
| 11 |
|
SC Halberg Brebach | 16 | 7 | 3 | 6 | 25:28 | -3 | 24 |
| 12 |
|
1. FSV Mainz 05 II | 15 | 7 | 1 | 7 | 29:25 | 4 | 22 |
| 13 |
|
SC 07 Idar-Oberstein | 15 | 6 | 4 | 5 | 17:19 | -2 | 22 |
| 14 |
|
Wormatia Worms | 15 | 6 | 3 | 6 | 29:26 | 3 | 21 |
| 15 |
|
FC 08 Homburg | 15 | 4 | 5 | 6 | 32:24 | 8 | 17 |
| 16 |
|
Hassia Bingen | 16 | 4 | 3 | 9 | 18:41 | -23 | 15 |
| 17 |
|
Rot-Weiß Hasborn | 16 | 2 | 5 | 9 | 10:30 | -20 | 11 |
| 18 |
|
SV Mettlach | 15 | 3 | 2 | 10 | 8:36 | -28 | 11 |
| 19 |
|
1. FC Saarbrücken II | 16 | 2 | 3 | 11 | 16:33 | -17 | 9 |
| 20 |
|
Germania Metternich | 15 | 1 | 2 | 12 | 9:42 | -33 | 5 |
