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| 25/11/2000 | FSV Salmrohr | - | Sportfreunde Eisbachtal | 2:3 | ||
| SC Halberg Brebach | - | 1. FSV Mainz 05 II | 2:2 | |||
| 1. FC Saarbrücken II | - | Rot-Weiß Hasborn | 4:2 | |||
| Germania Metternich | - | FK Pirmasens | 0:2 | |||
| Wormatia Worms | - | FC 08 Homburg | 1:1 | |||
| 1. FC Kaiserslautern II | - | Eintracht Bad Kreuznach | 4:0 | |||
| SV Mettlach | - | VfL Hamm/Sieg | 0:3 | |||
| SC Hauenstein | - | TuS Koblenz | 1:1 | |||
| 17/02/2001 | Hassia Bingen | - | Borussia Neunkirchen | 1:1 |
| » Tables | Home | Away | First round | Second round |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Kaiserslautern II | 22 | 15 | 5 | 2 | 52:13 | 39 | 50 |
| 2 |
|
FK Pirmasens | 22 | 12 | 5 | 5 | 35:18 | 17 | 41 |
| 3 |
|
VfL Hamm/Sieg | 22 | 13 | 1 | 8 | 40:25 | 15 | 40 |
| 4 |
|
Sportfreunde Eisbachtal | 22 | 11 | 6 | 5 | 34:29 | 5 | 39 |
| 5 |
|
Borussia Neunkirchen | 21 | 11 | 4 | 6 | 41:22 | 19 | 37 |
| 6 |
|
FSV Salmrohr | 22 | 10 | 7 | 5 | 33:21 | 12 | 37 |
| 7 |
|
EGC Wirges | 21 | 11 | 3 | 7 | 43:26 | 17 | 36 |
| 8 |
|
TuS Koblenz | 22 | 9 | 9 | 4 | 37:22 | 15 | 36 |
| 9 |
|
FC 08 Homburg | 22 | 9 | 7 | 6 | 49:30 | 19 | 34 |
| 10 |
|
Wormatia Worms | 22 | 9 | 5 | 8 | 41:36 | 5 | 32 |
| 11 |
|
1. FSV Mainz 05 II | 21 | 9 | 4 | 8 | 37:31 | 6 | 31 |
| 12 |
|
SC Hauenstein | 21 | 9 | 4 | 8 | 32:31 | 1 | 31 |
| 13 |
|
Eintracht Bad Kreuznach | 22 | 8 | 6 | 8 | 27:33 | -6 | 30 |
| 14 |
|
SC Halberg Brebach | 22 | 8 | 5 | 9 | 30:37 | -7 | 29 |
| 15 |
|
SC 07 Idar-Oberstein | 21 | 6 | 6 | 9 | 22:30 | -8 | 24 |
| 16 |
|
SV Mettlach | 22 | 5 | 4 | 13 | 15:44 | -29 | 19 |
| 17 |
|
Hassia Bingen | 22 | 4 | 6 | 12 | 20:55 | -35 | 18 |
| 18 |
|
1. FC Saarbrücken II | 22 | 3 | 4 | 15 | 25:45 | -20 | 13 |
| 19 |
|
Rot-Weiß Hasborn | 22 | 2 | 7 | 13 | 16:43 | -27 | 13 |
| 20 |
|
Germania Metternich | 21 | 3 | 2 | 16 | 14:52 | -38 | 11 |
