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| 20/08/2021 | 18:00 | Bayern München II | - | SpVgg Unterhaching | 5:1 (1:1) | |
| 18:00 | SC Eltersdorf | - | 1. FC Schweinfurt 05 | 0:4 (0:3) | ||
| 18:00 | FV Illertissen | - | TSV Aubstadt | 1:2 (1:1) | ||
| 18:00 | SV Heimstetten | - | Viktoria Aschaffenburg | 4:0 (3:0) | ||
| 18:30 | FC Memmingen | - | TSV 1860 Rosenheim | 4:0 (1:0) | ||
| 21/08/2021 | 13:00 | 1. FC Nürnberg II | - | TSV 1896 Rain | 0:1 (0:1) | |
| 13:00 | FC Augsburg II | - | TSV Buchbach | 0:0 (0:0) | ||
| 16:00 | Wacker Burghausen | - | SpVgg Greuther Fürth II | 1:4 (0:1) | ||
| 16:00 | FC Pipinsried | - | SV Schalding-Heining | 3:0 (2:0) | ||
| 16:00 | VfB Eichstätt | - | SpVgg Bayreuth | 1:3 (0:2) |
| » Tables | Home | Away | First round | Second round | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SpVgg Bayreuth | 9 | 8 | 0 | 1 | 31:10 | 21 | 24 |
| 2 |
|
Bayern München II | 9 | 7 | 1 | 1 | 33:10 | 23 | 22 |
| 3 |
|
1. FC Schweinfurt 05 | 9 | 5 | 3 | 1 | 28:12 | 16 | 18 |
| 4 |
|
Wacker Burghausen | 9 | 5 | 1 | 3 | 25:14 | 11 | 16 |
| 5 |
|
TSV Buchbach | 9 | 4 | 4 | 1 | 13:5 | 8 | 16 |
| 6 |
|
SpVgg Unterhaching | 9 | 5 | 1 | 3 | 14:15 | -1 | 16 |
| 7 |
|
TSV Aubstadt | 9 | 4 | 3 | 2 | 16:11 | 5 | 15 |
| 8 |
|
VfB Eichstätt | 9 | 4 | 2 | 3 | 18:17 | 1 | 14 |
| 9 |
|
FV Illertissen | 9 | 3 | 4 | 2 | 13:9 | 4 | 13 |
| 10 |
|
FC Pipinsried | 9 | 4 | 1 | 4 | 15:17 | -2 | 13 |
| 11 |
|
Viktoria Aschaffenburg | 9 | 4 | 1 | 4 | 11:16 | -5 | 13 |
| 12 |
|
FC Memmingen | 9 | 3 | 2 | 4 | 17:20 | -3 | 11 |
| 13 |
|
SV Heimstetten | 9 | 3 | 1 | 5 | 13:14 | -1 | 10 |
| 14 |
|
1. FC Nürnberg II | 9 | 2 | 3 | 4 | 13:13 | 0 | 9 |
| 15 |
|
SV Schalding-Heining | 9 | 2 | 3 | 4 | 8:15 | -7 | 9 |
| 16 |
|
FC Augsburg II | 9 | 2 | 2 | 5 | 12:19 | -7 | 8 |
| 17 |
|
SpVgg Greuther Fürth II | 9 | 1 | 3 | 5 | 12:23 | -11 | 6 |
| 18 |
|
TSV 1860 Rosenheim | 9 | 1 | 3 | 5 | 6:25 | -19 | 6 |
| 19 |
|
SC Eltersdorf | 9 | 1 | 2 | 6 | 10:22 | -12 | 5 |
| 20 |
|
TSV 1896 Rain | 9 | 1 | 2 | 6 | 5:26 | -21 | 5 |
| Promotion | |
| Playoffs | |
| Relegation |
